Vitamins : biology notes psc-junior lab assisstant

 

Vitamins 

Biology Notes 

Vitamins are essential nutrients and organic compounds found in foods that are crucial for maintaining proper health & functioning of the body. The term "Vitamin" was derived from the word "vitamine" coined by biochemist Casimir Funk in 1912. 

But it was  Sir Frederick Gowland Hopkins who is credited with the discovery of essential nutrient factors, now known as Vitamins, for which he was awarded the Nobel Prize in Physiology in 1929.

 

He also discovered the amino acid tryptophan, in 1901.

Of the 13 globally recognized vitamins, there are two different types. They are fat-soluble vitamins and water-soluble vitamins.

Fat-soluble Vitamins

Fat-soluble vitamins are vitamins that can be dissolved in fat before they get absorbed into the bloodstream to carry out their functions. Excesses of these vitamins are stored in the liver and are not needed every day in the diet. They are:

• Vitamin A – Retinol – Night Blindness, Xerophthalmia, Rough & Dry Skin
• Vitamin D – Calciferol – Rickets, Osteomalacia
• Vitamin E – Tocopherol – Mild hemolytic anemia in newborn infants.
• Vitamin K – Phylloquinone – Delay in Blood Clotting

Water-soluble Vitamins

Nine water-soluble vitamins — vitamin B-complex group and vitamin C — are found in the human diet:

• Vitamin B1 (Thiamine) – Beriberi, Wernicke-Korsakoff Syndrome 
• Vitamin B2 (Riboflavin) – Ariboflavinosis
• Vitamin B3 (Niacin) –Pellagra
• Vitamin B5 (Pantothenic acid) – Paresthesia
• Vitamin B6 (Pyridoxine) – Anaemia
• Vitamin B7 (Biotin) – Dermatitis, Enteritis
• Vitamin B9 (Folic Acid) – Malnutrition in the growth and development of the fetus during Pregnancy
• Vitamin B12 (Cobalamin) – Pernicious anemia ( a type of Megaloblastic anemia)
• Vitamin C (Ascorbic Acid) – Scurvy 

Vitamins, Sources & their functions

Provitamin: any ingested substance that an organism can transform into a vitamin. 
Antivitamin: any substance that interferes with the metabolic action of a vitamin.
Antioxidant vitamins: any substance that prevents cell damage due to aging. The three major antioxidant vitamins are beta-carotene, vitamin C, and vitamin E.
Brain vitamins: Vitamin B6, B9, and B12 are essential for the proper functioning of the brain. 

Vitamins, Year of Discovery & Discovered By

Year	Vitamin	Discovered by
1912	Vitamin A	Frederick Gowland Hopkins
1910	Vitamin B1	Casimir Funk
1920	Vitamin C	Albert Szent-Györgyi
1920	Vitamin D	Sir Edward Mellanby
1920	Vitamin B2	Alexander Wynter Blyth
1922	Vitamin E	Herbert McLean Evans
1929	Vitamin K1	Henrik Dam
1931	Vitamin B5	Roger J. Williams
1931	Vitamin B7	Vincent du Vigneaud
1934	Vitamin B6	Paul György
1936	Vitamin B3	Conrad Arnold Elvehjem
1941	Vitamin B9	Lucy Wills
1948	Vitamin B12	Various scientists

📝 ExtraNotes:

• Father of vitamin therapy – Casimir Funk.
• Disease that used to be known as "the English Disease" – Rickets.
• The organ which stores fat-soluble vitamins – Liver.
• First artificially developed Vitamin – Vitamin C.
• Vitamin known as Sunshine Vitamin – Vitamin D.
• Another name of Vitamin H – Vitamin B7.
• Vitamin known as Fresh Food Vitamin and Anti Cancer Vitamin – Vitamin C.
• Vitamin produces collagen– Vitamin C.
• Vitamin produces melanin– Vitamin C & E.
• Which disease is also known as Sailor Plague – Scurvy.
• The overdose of which vitamin causes Liver damage – Vitamin B3.
• The presence of cobalt in vitamin B12 was established for the first time by –Borax-Bead test.
• Test for Night Blindness – Rose Bengal Test.
• Vitamin used for ELISA test (AIDS) – Vitamin B7 (Biotin).
• Vitamin that helps in the absorption of Calcium – Vitamin D.
• Vitamin that helps in healing wound –Vitamin C.
• Vitamin that helps in blood clotting – Vitamin K. 
• The structure analog of vitamin K, which is used as an anticoagulant– Warfarin.
• Vitamin is also called as Pyridoxine – Vitamin B6.
• Pyridoxine is a mix of how many derivatives – 3 (Pyridoxal, Pyridoxine & Pyridoxamine).
• Deficiency of vitamin B6 causes – Eczema.
• Deficiency of which vitamin causes Cerebral Hemorrhage – Vitamin K.
• The deficiency of which group of vitamins affects the skin – Vitamin B (Riboflavin, Niacin, Pyridoxine, Pantothenic Acid).
• Overdose of which vitamin causes the disease Hypervitaminosis (abnormally high storage levels of vitamins which leads to toxicity) – Vitamin A.
• Vitamin that slows down the progression of Alzheimer’s disease – Vitamin B.
• Vitamin that serves as a hormone precursor – Vitamin D.
• A deficiency which vitamin causes Bowlegs, knocknee and pigeon chest in children – Vitamin D.

READ MORE: COMMON HUMAN DISEASE AND AFFECTED BODY PARTS